| Katy Wilson & Matt Cassar | | | |
| vs |
| Katy Wilson & Matt Cassar |
03/12/2021 6-0, 6-0 |
| Bye |
| | Katy Wilson & Matt Cassar |
| Dave Isles & Eisha Kaur Chandi | 17/12/2021 6-0, 6-0 |
19/11/2021 6-4, 6-0 |
| Dave Isles & Eisha Kaur Chandi |
| |
| Charlotte Clarke & Steve Rigg |
| | Katy Wilson & Matt Cassar |
| Alyson Whitaker & William Johnson | 31/12/2021 6-4, 6-3 |
19/11/2021 1-6, 3-6 |
| Judith Hancock & Steve Mulliner |
03/12/2021 6-2, 3-6, 10-5 |
| Judith Hancock & Steve Mulliner |
| | Judith Hancock & Steve Mulliner |
| Catherine Hamilton & Simon Bradford | |
19/11/2021 7-5, 6-3 |
| Catherine Hamilton & Simon Bradford |
| |
| Rafael Mercader & Sophie Purser |
| |
| Elsabe Ramos & Jordan Glossop |
19/11/2021 0-6, 3-6 |
| Mark Bowyer & Stephanie Eadon |
03/12/2021 2-6, 3-6 |
| Mark Bowyer & Stephanie Eadon |
| | Hilary Coyle & Lee Marshall |
| Jack Morrow & Larisa Marcu | 17/12/2021 6-3, 6-3 |
19/11/2021 1-6, 2-6 |
| Hilary Coyle & Lee Marshall |
| |
| Hilary Coyle & Lee Marshall |
| | Hilary Coyle & Lee Marshall |
| Jared Lacey & Liz Taulbut | |
19/11/2021 6-2, 2-6, 10-7 |
| Jared Lacey & Liz Taulbut |
03/12/2021 2-6, 2-6 |
| Jane Taylor & Magnus Redgrave |
| | Kylie Holmes & Simon Toms |
| Bye | |
| vs |
| Kylie Holmes & Simon Toms |
| |
| Kylie Holmes & Simon Toms |